Extracellular Vesicle (EV) Therapeutics

Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their communicative capabilities that may serve as biomarkers, therapeutic agents and drug delivery systems.

EVs are nano-particles that secrete from almost all living cells and which contain bioactive substances such as nucleic acids (microRNA, messenger RNA and DNA), proteins and other intracellular substances. EVs are found in bodily fluids such as blood, urine and saliva. EVs create pharmacological effects when they reach target cells.

Major advantages of EV therapies involving exosomes include the multifunctional (multimodal) nature of their medicinal components and their ability to serve as a drug delivery system. The multifunctional molecules contained in EVs can target multiple RNAs, which can be effective against diseases with complex pathologies that have historically been difficult to treat.

EVs and their Future Applications

EVs, including exosomes, are responsible for intercellular communication via their bioactive substances. In living organisms, secreted vesicles are transported through bodily fluids where they deliver functional molecules to receiving cells.

EVs appear to have anti-inflammatory, immunoregulatory and tissue repair capabilities, while also being linked to cancer and neurodegenerative diseases.

EVs circulate in the body and are present in various bodily fluids such as blood and urine. They contain information derived from the cells that release them and potentially can be developed as biomarkers, therapeutic agents and drug delivery systems.

Extracellular Vesicle (EV) Therapeutics

EVs and their Future Applications

EVs, including exosomes, are responsible for intercellular communication via their bioactive substances. In living organisms, secreted vesicles are transported through bodily fluids where they deliver functional molecules to receiving cells.

EVs appear to have anti-inflammatory, immunoregulatory and tissue repair capabilities, while also being linked to cancer and neurodegenerative diseases.

EVs circulate in the body and are present in various bodily fluids such as blood and urine. They contain information derived from the cells that release them and potentially can be developed as biomarkers, therapeutic agents and drug delivery systems.

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